Article
Genetic variations in zona pellucida glycoproteins: Implications for fertility and ART outcomes.
Mutation research. Reviews in mutation research - 1 Jan 2025
Rajput Neha, Gahlay Gagandeep Kaur
Abstract excerpt
The success of Assisted Reproductive Technologies (ART), such as IVF and ICSI, relies heavily on the health of the oocyte, with abnormalities in oocyte morphology often leading to ART failure. The zona pellucida (ZP), an extracellular matrix surrounding the oocyte, plays a crucial role in sperm-egg recognition, species-specific fertilization, and protecting the embryo until implantation. This article investigates...
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