Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A recurrent North African ZP1 variant and a literature review of genotype-phenotype correlations in ZP-related infertility.

Journal of assisted reproduction and genetics - 1 Jun 2026

Nourine Besma Hibat Allah, Ounis Leyla, Lang Cécile, Feyereisen Laura, Zoghmar Abdelali, Milat Houssem Eddine, Rouabah Leila, Mayer Claudine, Viville Stéphane

Abstract excerpt

PURPOSE: Genetic diagnosis is increasingly crucial in medically assisted reproduction (MAR), enabling identification of infertility causes and guiding personalized treatments. This study investigates the genetic basis of empty follicle syndrome (EFS) in two independent consanguineous Algerian families with primary infertility. METHODS: Exome sequencing and in silico analysis of a comprehensive infertility gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa, Northern
Share to Consanguinity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exome Sequencing

Share to Genetic Association Studies

Share to Infertility, Female

Share to Oocytes

Share to Pregnancy

Share to Reproductive Techniques, Assisted

Source

Open in PubMed Open full text

Identifiers

PMID: 42060237
DOI: 10.1007/s10815-026-03886-2
PMCID: PMC13319846

Genes

ZP1
EFS
ZP2
ZP3
ZP4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A recurrent North African ZP1 variant and a literature review of genotype-phenotype correlations in ZP-related infertility.PMID 42060237Read ↗

Novel variants in ZP1, ZP2 and ZP3 associated with empty follicle syndrome and abnormal zona pellucida.Semantic proximity Read ↗

Heterozygous mutations in ZP1 and ZP3 cause formation disorder of ZP and female infertility in human.Semantic proximity Read ↗

Case report: A novel homozygous variant in ZP3 is associated with human empty follicle syndromeSemantic proximity Read ↗

Compound heterozygous <i>ZP1</i> mutations cause empty follicle syndrome in infertile sistersSemantic proximity Read ↗

Compound heterozygous ZP1 mutations cause empty follicle syndrome in infertile sistersSemantic proximity Read ↗

A Novel Homozygous Missense ZP1 Variant Result in Human Female Empty Follicle Syndrome.Semantic proximity Read ↗

Novel mutations in ZP2 and ZP3 cause female infertility in three patients.Semantic proximity Read ↗

Novel mutations in ZP1 and ZP2 cause primary infertility due to empty follicle syndrome and abnormal zona pellucida.Semantic proximity Read ↗

A ZP1 gene mutation in a patient with empty follicle syndrome: A case report and literature review.Semantic proximity Read ↗

A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS)Semantic proximity Read ↗

Homozygous Splice Site Mutation in ZP1 Causes Familial Oocyte Maturation Defect.Semantic proximity Read ↗

A Novel Homozygous Nonsense Mutation in ZP1 Causes Female Infertility due to Empty Follicle Syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.