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Article

Host Genetic Factors and Clinical Comorbidities Associated With Tuberculosis Risk.

HLA - 1 Sept 2025

Lin Shih-Ping, Chen I-Chieh, Lin Ching-Heng, Hsiao Tzu-Hung, Liu Po-Yu, Chen Yi-Ming

Abstract excerpt

HLA influence the immune response, shaping genetic susceptibility or resistance to tuberculosis (TB). This study aimed to investigate the associations of host genetics and comorbidities with TB infection in Taiwanese populations. This retrospective case-control study utilised data from the Taiwan Precision Medicine Initiative. TB cases and non-TB controls were compared using genome-wide association studies...

Read the complete abstract on PubMed

Topics

Humans
Male
Female
Genetic Predisposition to Disease
Middle Aged
Case-Control Studies
Risk Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Tuberculosis

Taiwan

Comorbidity

Genome-Wide Association Study

Retrospective Studies

HLA-DRB1 Chains

Aged

Smoking

Adult

Diabetes Mellitus

Genotype

Source

Identifiers

PMID: 40891148
DOI: 10.1111/tan.70384

Provenance

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