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Role of Fibroblast‐Immune Crosstalk in Kidney, Lung, and Skin Tertiary Lymphoid Structures

29 Aug 2025

Abstract excerpt

Tertiary lymphoid structures (TLSs) are organized aggregates of lymphocytes, myeloid cells, and stromal cells that form at sites of inflammation, providing adaptive immune responses outside of secondary lymphoid organs (SLOs). Found in various pathological conditions-including chronic infections, cancer, organ transplantation, autoimmune diseases, and allergy-the presence of TLSs is linked to potentiation of...

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PMID: 40884054
DOI: 10.1111/imr.70059

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