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Fibroblast heterogeneity and tertiary lymphoid tissues in the kidney

5 May 2021

Abstract excerpt

Fibroblasts reside in various organs and support tissue structure and homeostasis under physiological conditions. Phenotypic alterations of fibroblasts underlie the development of diverse pathological conditions, including organ fibrosis. Recent advances in single-cell biology have revealed that fibroblasts comprise heterogeneous subpopulations with distinct phenotypes, which exert both beneficial and detrimental...

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PMID: 33951198
DOI: 10.1111/imr.12969

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