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Article

Minigenome System to Study Respiratory Syncytial Virus Transcription Versus Genome Replication.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2025

Kim Heesu, Noton Sarah L

Abstract excerpt

The respiratory syncytial virus (RSV) minigenome system is a powerful analytical tool that has enabled viral transcription and genome replication to be modeled in a cellular context without viral infection. The minigenome assay can be used to dissect the different steps in RSV transcription and genome replication, assess the effects of mutations in cis-acting RNA elements, analyze mutations in the polymerase and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40879905
DOI: 10.1007/978-1-0716-4666-3_8

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