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Capillary Endothelial Cell Subtypes in the Lung: Markers and Response to Developmental Lung Injury

18 Aug 2025

Abstract excerpt

Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Disrupted microvascular growth is a well-recognized pathologic feature of BPD, which plays a critical role in arrested alveologenesis. Recent studies have identified two subpopulations of pulmonary microvascular endothelial cells (ECs): general capillary (gCap) and aerocyte (aCap) cells. In this study, we validated proposed...

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PMID: 40845320
DOI: 10.1165/rcmb.2025-0009oc

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