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A molecular systems architecture of the mesenchymal stromal cell microenvironment

22 Aug 2025

Abstract excerpt

A systems-level understanding of immunomodulatory, regenerative, and pro-/antifibrosis functions of mesenchymal stromal cells (MSCs) is critical to advance MSCs as a viable therapeutic option. Given the complexity of MSCs and their interactions with microenvironmental cells, a systems biology approach may enable such understanding to achieve practical objectives such as target identification, combination...

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PMID: 40843515
DOI: 10.1093/stmcls/sxaf042

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