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Article

A systems biology approach to identify niche determinants of cellular phenotypes.

Stem cell research - 1 Sept 2016

Ravichandran Srikanth, Okawa Satoshi, Martínez Arbas Susana, Del Sol Antonio

Abstract excerpt

Recent reports indicate a dominant role for cellular microenvironment or niche for stably maintaining cellular phenotypic states. Identification of key niche mediated signaling that maintains stem cells in specific phenotypic states remains a challenge, mainly due to the complex and dynamic nature of stem cell-niche interactions. In order to overcome this, we consider that stem cells maintain their phenotypic...

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Identifiers

PMID: 27649532
DOI: 10.1016/j.scr.2016.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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