Article
Cerebrospinal Fluid Mononuclear Cell Phenotype and Activation Predictors of 2-Week and 1-Year Survival Among Persons With HIV-Associated Cryptococcal Meningitis.
The Journal of infectious diseases - 14 Nov 2025
Rutakingirwa Morris K, Ssebambulidde Kenneth, Okurut Samuel, Kwizera Richard, Nabwana Martin, Gakuru Jane, Ndyetukira Jane Francis, Mulwana Suzan, Nankungu Lydia, Tadeo Kizza K, Musubire Abdu K, Boulware David R, Meya David B
Abstract excerpt
BACKGROUND: Despite efforts to optimize therapy for HIV-associated cryptococcal meningitis (CM), survival outcomes remain poor. It is unclear how the cerebrospinal fluid (CSF) cellular immune phenotype and activation contribute to 2-week and 1-year survival following CM. METHODS: We compared baseline CSF mononuclear cell phenotype and activation among adults with HIV-associated CM who died within 2 weeks of CM...
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