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CRISPR-based assays for the detection of BK virus and JC virus infections post-kidney transplantation

4 Aug 2025

Abstract excerpt

BACKGROUND: Organ transplantation recipients encounter significant risks from acute or chronic infections that threaten graft survival. BK virus (BKV) and JC virus (JCV) are two prominent opportunistic infection viruses, and they may cause polyomavirus-associated nephropathy and graft kidney loss in patients who are in an immunosuppressed state after kidney transplantation. Hence, timely detection and sustained...

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PMID: 40760679
DOI: 10.1186/s40779-025-00632-0

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