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Modulation of Ferroptosis by microRNAs in Human Cancer

24 Apr 2023

Abstract excerpt

Ferroptosis is a cell death pathway triggered by an imbalance between the production of oxidants and antioxidants, which plays an emerging role in tumorigenesis. It is mainly regulated at three different levels including iron metabolism, the antioxidant response, and lipid metabolism. Epigenetic dysregulation is a "hallmark" of human cancer, with nearly half of all human cancers harboring mutations in epigenetic...

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PMID: 37240889
DOI: 10.3390/jpm13050719

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