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Article

Clinicopathologic and Molecular Analysis of Primary Angiosarcoma of Bone-A Single Institution Experience.

Genes, chromosomes & cancer - 1 Jun 2025

Hirose Takeshi, Chang Hsin-Yi, Lefkowitz Robert A, Healey John, Antonescu Cristina R

Abstract excerpt

PURPOSE: Bone angiosarcoma (B-AS) is an exceedingly rare and aggressive vascular neoplasm, with limited therapeutic options and poor outcomes. Unlike the more prevalent clinical subsets (breast, head and neck), the pathogenesis of B-AS remains poorly defined, with no targeted therapeutic strategies available. Moreover, the often delays in diagnosis, either radiographically or pathologically, as well as the common...

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Source

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Identifiers

PMID: 40492503
DOI: 10.1002/gcc.70056
PMCID: PMC12720482

Genes

KDR
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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