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Article

Direct letters to relatives at risk of hereditary cancer-a randomised trial on healthcare-assisted versus family-mediated risk disclosure.

European journal of human genetics : EJHG - 1 Oct 2025

Ehrencrona Hans, Öfverholm Anna, Hawranek Carolina, Lovmar Lovisa, Svensson Sara, Wennstedt Sigrid, Hellquist Barbro, Rosén Anna

Abstract excerpt

Observational studies suggest that direct contact from healthcare to at-risk relatives may increase genetic counselling (GC) uptake as compared to family-mediated risk disclosure, but randomised controlled trials (RCTs) are lacking. This study assessed whether the offer of direct letters to relatives at risk of hereditary breast and ovarian cancer (HBOC) or Lynch syndrome increases GC uptake compared to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40745491
DOI: 10.1038/s41431-025-01922-w
PMCID: PMC12480553

Genes

GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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