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Health System-Led Early Consent and Direct Contact of At-Risk Relatives: Pilot Study Results.

Public health genomics - 1 Jan 2025

Henrikson Nora B, Scrol Aaron, Zepp Jamilyn M, Anderson Melissa L, Blasi Paula R, Ewing John J, Grafton Jane, Ralston James D, Fullerton Stephanie M, Leppig Kathleen A

Abstract excerpt

INTRODUCTION: At-risk relatives of probands with genetic variants associated with hereditary cancer risk should receive cascade genetic testing. In the USA, probands are expected to notify their own at-risk relatives, but many relatives never learn of their risk, representing missed opportunity to reduce morbidity and mortality associated with hereditary cancers. Direct contact of relatives could reach relatives...

Topics

Humans
Pilot Projects
Male
Female
Adult
Genetic Counseling
Middle Aged
Genetic Testing
Genetic Predisposition to Disease
Family
Prospective Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Aged

Informed Consent

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Open in PubMed Open full text

Identifiers

PMID: 40179849
DOI: 10.1159/000545404
PMCID: PMC12074871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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