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Health System-Led Early Consent and Direct Contact of At-Risk Relatives: Pilot Study Results.

Public health genomics - 1 Jan 2025

Henrikson Nora B, Scrol Aaron, Zepp Jamilyn M, Anderson Melissa L, Blasi Paula R, Ewing John J, Grafton Jane, Ralston James D, Fullerton Stephanie M, Leppig Kathleen A

Abstract excerpt

INTRODUCTION: At-risk relatives of probands with genetic variants associated with hereditary cancer risk should receive cascade genetic testing. In the USA, probands are expected to notify their own at-risk relatives, but many relatives never learn of their risk, representing missed opportunity to reduce morbidity and mortality associated with hereditary cancers. Direct contact of relatives could reach relatives...

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Identifiers

PMID: 40179849
DOI: 10.1159/000545404
PMCID: PMC12074871

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