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Article

Integrative multi-omics data from early development to identify the genes and cell types underlying attention-deficit/hyperactivity disorder.

BMC psychiatry - 30 Jul 2025

Jiao Shufen, Bao Li, Lu Xiaowen, Wu Yong, Li Yichen

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWASs) have identified numerous loci significantly associated with attention-deficit/hyperactivity disorder (ADHD); however, the majority of these loci are located in non-coding regions, limiting our understanding of the disorder's underlying pathogenesis. METHODS: We applied the summary data-based Mendelian randomization (SMR) approach to integrate expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40739630
DOI: 10.1186/s12888-025-07209-0
PMCID: PMC12312303

Genes

LSM6
RPS26

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