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Genotypic and Phenotypic Methods in the Detection of MDR-TB and Evolution to XDR-TB

21 Jul 2025

Abstract excerpt

Background: Accurate and rapid diagnosis of drug-resistant tuberculosis is essential for initiating appropriate treatment and preventing the transmission of these strains. This study compares phenotypic and genotypic methods of drug susceptibility testing for Mycobacterium tuberculosis (M. tuberculosis). Methods: Resistance to first-line drugs, as well as resistance to second-line drugs (fluoroquinolones and...

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PMID: 40724033
DOI: 10.3390/antibiotics14070732

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