Article
Genetic predisposition to unwanted side effects under antidepressants and antipsychotics: a molecular-genetic study of 902 patients over 6 weeks.
European archives of psychiatry and clinical neuroscience - 1 Mar 2026
Stassen Hans H, Bachmann S, Bridler R, Cattapan K, Hartmann A M, Rujescu D, Seifritz E
Abstract excerpt
This project aimed at (1) detailing the complex side effect patterns of 902 inpatients treated for major depression or schizophrenia under polypharmacy regimens; (2) developing a quantitative side effect model that accounts for the various facets of clinically observable adverse events; and (3) analyzing irregularities in genetic diversity through multidimensional "gene vectors" in order to reveal possible...
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