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Vibrio cholerae lineage and pangenome diversity vary geographically across Bangladesh over 1 year.

Microbial genomics - 1 Jul 2025

Qin Chuhan, Lypaczewski Patrick, Sayeed Md Abu, Cuénod Aline, Brinkley Lindsey, Creasy-Marrazzo Ashton, Cato Emilee T, Islam Kamrul, Khabir Md Imam Ul, Bhuiyan Md Taufiqur R, Begum Yasmin, Kamat Manasi N, Bailey Laura S, Basso Kari B, Qadri Firdausi, Khan Ashraful I, Nelson Eric J, Shapiro B Jesse

Abstract excerpt

Cholera is an acute diarrhoeal disease caused by Vibrio cholerae. It remains a major public health challenge worldwide, and particularly in the endemic region around the Bay of Bengal. Over decadal time scales, one lineage typically dominates and spreads in global pandemic waves. However, it remains unclear to what extent diverse lineages co-circulate during a single outbreak. Defining the pool of diversity over...

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Identifiers

PMID: 40709915
DOI: 10.1099/mgen.0.001437
PMCID: PMC12452190

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