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Article

Associations of Anthropometric Indicators with Bone Mineral Density and the Risk of Bone Fractures and Falls: A Large-Scale Genetic Correlation Study.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Hu Xiao, Gao Zhao-Xing, Zhu Yan-Yu, Li Sheng, Ding Wen-Wen, Pan Hai-Feng, Wang Peng

Abstract excerpt

INTRODUCTION: Although observational studies have suggested potential associations between Anthropometric Indicators (AIs), Osteoporosis (OP), and bone fractures, the causal links are still scarce. This study aimed to comprehensively evaluate the causal relationships between five AIs and site- and age-specific Bone Mineral Density (BMD), as well as bone fractures and falls. METHODS: Genetic exposure data for AIs...

Read the complete abstract on PubMed

Topics

Humans
Bone Density
Accidental Falls
Polymorphism, Single Nucleotide
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Risk Factors

Female

Genome-Wide Association Study

Fractures, Bone

Male

Middle Aged

Anthropometry

Aged

Osteoporosis

Waist Circumference

Source

Open in PubMed Open full text

Identifiers

PMID: 40692145
DOI: 10.2174/0118715303369995250702111723
PMCID: PMC13670186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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