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NR1D1 (REVERBalpha) may be novel candidate gene for coronary artery disease in men: Differential effects of NR1D1 polymorphisms by gender.

Chronobiology international - 1 Sept 2025

Yesil Rukiye, Aydogan Cagatay, Ozkara Gulcin, Tokat Bengu, Yildiz Ahmet, Ebeoglu Abdullah Omer, Seyhan Mehmet Fatih, Ozturk Oguz, Yilmaz-Aydogan Hulya

Abstract excerpt

Circadian rhythms are strongly linked to cardiometabolic syndromes such as coronary artery disease (CAD). NR1D1(REVERBalpha) regulates lipid metabolism and circadian clock. This study investigated possible associations between the NR1D1 rs2314339 C > T and rs72836608 C > A polymorphisms and metabolic parameters in 126 CAD patients and 125 controls. Allelic discrimination was performed by Real-Time PCR using...

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Identifiers

PMID: 40686381
DOI: 10.1080/07420528.2025.2532797

Genes

CAD
NR1D1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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