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Article

SpatioMark: quantifying the impact of spatial proximity on cell phenotype.

Bioinformatics (Oxford, England) - 2 Aug 2025

Iyengar Sourish S, Qin Alex R, Robertson Nicholas, Harman Andrew N, Patrick Ellis

Abstract excerpt

MOTIVATION: As research advances in spatially resolving the biological archetype of various diseases, technologies that capture the spatial relationships between cells are demonstrating increasing value. Whilst there are an increasing number of analytical methods being developed to identify the complex web of interactions between cells, the downstream impacts of these cell-cell relationships are under explored....

Read the complete abstract on PubMed

Topics

Humans
Software
Phenotype
Proteomics
Gene Expression Profiling
Computational Biology
Transcriptome

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Identifiers

PMID: 40674581
DOI: 10.1093/bioinformatics/btaf409
PMCID: PMC12343047

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