Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Renal tubular VMP1 protects against acute kidney injury via modulating autophagy and autophagy-independent pathway

15 Jul 2025

Abstract excerpt

Macroautophagy/autophagy activation protects renal proximal tubular epithelial cells (PTECs) against acute kidney injury (AKI) induced by various challenges. The mechanism that regulates autophagy in PTECs, however, remains incompletely understood. Here, we report that VMP1 (vacuole membrane protein 1) plays an essential role in enabling PTECs to maintain high autophagic flow under AKI conditions. VMP1 in PTECs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Glycation End Products research
Share to Autophagy in Disease and Therapy
Share to Cannabis and Cannabinoid Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40660473
DOI: 10.1080/15548627.2025.2533306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Renal tubular VMP1 protects against acute kidney injury via modulating autophagy and autophagy-independent pathwayPMID 40660473Read ↗

YME1L-mediated mitophagy protects renal tubular cells against cellular senescence under diabetic conditionsSemantic proximity Read ↗

Mitophagy Regulates Kidney DiseasesSemantic proximity Read ↗

Emerging role of autophagy in kidney function, diseases and agingSemantic proximity Read ↗

The role of mitophagy in the development of chronic kidney diseaseSemantic proximity Read ↗

From Physiology to Pathology: The Role of Mitochondria in Acute Kidney Injuries and Chronic Kidney DiseasesSemantic proximity Read ↗

Autophagy in kidney disease and aging: lessons from rodent modelsSemantic proximity Read ↗

Decoding the Versatile Landscape of Autophagic Protein VMP1 in Cancer: A Comprehensive Review across Tissue Types and Regulatory MechanismsSemantic proximity Read ↗

αKlotho modulates BNIP3-mediated mitophagy by regulating FoxO3 to decrease mitochondrial ROS and apoptosis in contrast-induced acute kidney injurySemantic proximity Read ↗

Autophagy in Kidney Health and DiseaseSemantic proximity Read ↗

Transcriptome analysis of the potential mechanisms regulating autophagy in matrine- treated IMCD3 cellsSemantic proximity Read ↗

Nephron-specific knockin of the PIKfyve-binding-deficient Vac14L156R mutant results in albuminuria and mesangial expansion.Semantic proximity Read ↗

Mechanisms and implications of podocyte autophagy in chronic kidney diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.