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Article

Emerging role of autophagy in kidney function, diseases and aging

12 Jun 2012

Abstract excerpt

Autophagy is a highly conserved process that degrades cellular long-lived proteins and organelles. Accumulating evidence indicates that autophagy plays a critical role in kidney maintenance, diseases and aging. Ischemic, toxic, immunological, and oxidative insults can cause an induction of autophagy in renal epithelial cells modifying the course of various kidney diseases. This review summarizes recent insights...

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PMID: 22692002
DOI: 10.4161/auto.19821

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