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Article

DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy

9 Jul 2025

Abstract excerpt

BACKGROUND: Synovitis is a key factor in temporomandibular joint osteoarthritis (TMJOA) and could be an early sign of the disease. Notably, synovitis and its macrophage component represent a target of interest for developing treatments. Dental pulp stem cells (DPSCs) are derived from the neural crest, coincidentally with maxillofacial tissues, thus attracting significant interest in situ maxillofacial...

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PMID: 40629418
DOI: 10.1186/s13287-025-04468-2

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