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Impact of aging on primary liver cancer: epidemiology, pathogenesis and therapeutics

11 Oct 2021

Abstract excerpt

Aging involves progressive physiological and metabolic reprogramming to adapt to gradual deterioration of organs and functions. This includes mechanisms of defense against pre-malignant transformations. Thus, certain tumors are more prone to appear in elderly patients. This is the case of the two most frequent types of primary liver cancer, i.e., hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma...

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PMID: 34633987
DOI: 10.18632/aging.203620

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