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Animal studies on the modulation of differential efficacy of polyethylene glycol loxenatide by intestinal flora

19 Jun 2025

Abstract excerpt

Background: Gut microbiota has demonstrated an increasingly important role in the onset and development of type 2 diabetes mellitus (T2DM), Further investigations have revealed the interactions between drugs and the gut microbiome. However, there are still gaps in research regarding the potential interactions between the gut microbiota and GLP-1 and their therapeutic response in people with T2DM. In addition,...

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PMID: 40612440
DOI: 10.3389/fendo.2025.1508473

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