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Article

Fourteen composite probiotics alleviate type 2 diabetes through modulating gut microbiota and modifying M1/M2 phenotype macrophage in db/db mice.

Pharmacological research - 1 Nov 2020

Wang Yanming, Wu Yuche, Sailike Jialehasibieke, Sun Xin, Abuduwaili Nigare, Tuoliuhan Hapula, Yusufu Mulatiaize, Nabi Xin-Hua

Abstract excerpt

Dysregulation of intestinal microbiota accelerates the development of type 2 diabetes. Probiotics are potential adjunctive therapy in the treatment of diabetes. This study investigated the anti-diabetic mechanism of 14 composite probiotics. Results showed that treatment with 14 composite probiotics improved intestinal microbiota equilibrium by increasing the population of short-chain fatty acids (SCFAs)-producing...

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PMID: 32818655
DOI: 10.1016/j.phrs.2020.105150

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