Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bioinformatics-Based Discovery of Therapeutic Targets in Cadmium-Induced Lung Adenocarcinoma: The Role of Oxyresveratrol

3 Jul 2025

Abstract excerpt

In this study, we establish a comprehensive bioinformatic and experimental platform for revealing the molecular bases of cadmium (Cd)-induced lung adenocarcinoma (LUAD) and the therapeutic efficacy of the natural polyphenol oxyresveratrol (O-RES) against this disease. A total of 116 differentially expressed genes (DEGs) were obtained, including 30 upregulated and 86 downregulated obtained by integrating five...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers in Disease Mechanisms
Share to Ferroptosis and cancer prognosis
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40610695
DOI: 10.1007/s12011-025-04730-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bioinformatics-Based Discovery of Therapeutic Targets in Cadmium-Induced Lung Adenocarcinoma: The Role of OxyresveratrolPMID 40610695Read ↗

Mechanism of Colorectal Cancer Development under Exposure to Synthetic Phenolic Antioxidants Based on Network Toxicology and Molecular DockingSemantic proximity Read ↗

Analysis of Moonlighting Proteins Regulated by Curcumin and Resveratrol in CancerSemantic proximity Read ↗

In Silico Screening of Synthetic and Natural Compounds to Inhibit the Binding Capacity of Heavy Metal Compounds against EGFR Protein of Lung Cancer.Semantic proximity Read ↗

Identification of potential target genes of non-small cell lung cancer in response to resveratrol treatment by bioinformatics analysisSemantic proximity Read ↗

Uncovering the mechanism of resveratrol in the treatment of asthma: a network pharmacology approach with molecular docking and experimental validationSemantic proximity Read ↗

Identification of the Resveratrol Potential Targets in the Treatment of OsteoarthritisSemantic proximity Read ↗

SETBP1-R54P mutation promotes malignant transformation of cadmium-induced 16HBE cells by down-regulating circ_0007095 expression.Semantic proximity Read ↗

In silico toxicogenomic data-mining to unraveling the influence of lead and cadmium co-exposure on molecular mechanisms involved in the development and progression of HypertensionSemantic proximity Read ↗

Identification of the Resveratrol Potential Targets in the Treatment of OsteoarthritisSemantic proximity Read ↗

Potential targets of diosgenin for the treatment of oral squamous cell carcinoma and their bioinformatics and transcriptional profiling analysesSemantic proximity Read ↗

High-throughput prediction of nephrotoxicity in humans.Semantic proximity Read ↗

Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.