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Article

Identifying the Mechanisms of a Peripherally Limited Exercise Phenotype in Patients With Heart Failure With Preserved Ejection Fraction.

Circulation. Heart failure - 1 Aug 2024

Skow Rachel J, Sarma Satyam, MacNamara James P, Bartlett Miles F, Wakeham Denis J, Martin Zachary T, Samels Mitchel, Nandadeva Damsara, Brazile Tiffany L, Ren Jimin, Fu Qi, Babb Tony G, Balmain Bryce N, Nelson Michael D, Hynan Linda S, Levine Benjamin D, Fadel Paul J, Haykowsky Mark J, Hearon Christopher M

Abstract excerpt

BACKGROUND: We identified peripherally limited patients using cardiopulmonary exercise testing and measured skeletal muscle oxygen transport and utilization during invasive single leg exercise testing to identify the mechanisms of the peripheral limitation. METHODS: Forty-five patients with heart failure with preserved ejection fraction (70±7 years, 27 females) completed seated upright cardiopulmonary exercise...

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Identifiers

PMID: 39051098
DOI: 10.1161/CIRCHEARTFAILURE.123.011693
PMCID: PMC11335445

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