Article
[Experimental evaluation of the pathogenicity of Lassa virus variants].
Voprosy virusologii - 1 Jan 2000
Vladyko A S, Surikova L E, Vovk T A, Cherednichenko I A, Torop A V
Abstract excerpt
Pathogenicity for guinea pigs and white mice of various Lassa virus variants: native, having had 1 passage in Vero cell culture and 4 passages in newborn white mouse brain; a virus having gone through 10 passages in Vero cells and 8 mouse brain passages (variant No. 10); a small-plaque clone deri...
Topics
- Animals
- Animals, Newborn
- Arenaviridae
- Defective Viruses
- Genetic Variation
- Guinea Pigs
- Lassa virus
- Mice
- Mutation
- Phenotype
- Temperature
- Viral Interference
- Viral Plaque Assay
- Virulence
- Virus Cultivation