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Article

Prognostic and therapeutic value of a 23-gene risk score tailored to the molecular characteristics of mucinous colorectal cancer.

British journal of cancer - 1 Sept 2025

Seo Jee-Woo, Kim Jae-Yoon, Ha Ye Jin, Tak Ka Hee, Kim Jeong-Hwan, Cho Young-Bum, Park Seong-Hwan, Yoon Yong Sik, Kim Chan Wook, Lee Jong Lyul, Kim Seon-Young, Kim Seon-Kyu

Abstract excerpt

BACKGROUND: Mucinous adenocarcinoma (MuC), a colorectal cancer (CRC) subtype, exhibits distinct molecular features and poorer response to chemoradiotherapy than non-mucinous adenocarcinoma (NMuC). Conventional treatments often fail to address CRC heterogeneity, particularly in stage II disease. Therefore, improved biomarkers for risk stratification and personalised treatment are needed. METHODS: We analysed gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40603571
DOI: 10.1038/s41416-025-03104-3
PMCID: PMC12405609

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