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Article

Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jan 2011

Salazar Ramon, Roepman Paul, Capella Gabriel, Moreno Victor, Simon Iris, Dreezen Christa, Lopez-Doriga Adriana, Santos Cristina, Marijnen Corrie, Westerga Johan, Bruin Sjoerd, Kerr David, Kuppen Peter, van de Velde Cornelis, Morreau Hans, Van Velthuysen Loes, Glas Annuska M, Van't Veer Laura J, Tollenaar Rob

Abstract excerpt

PURPOSE: This study aims to develop a robust gene expression classifier that can predict disease relapse in patients with early-stage colorectal cancer (CRC). PATIENTS AND METHODS: Fresh frozen tumor tissue from 188 patients with stage I to IV CRC undergoing surgery was analyzed using Agilent 44K oligonucleotide arrays. Median follow-up time was 65.1 months, and the majority of patients (83.6%) did not receive...

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PMID: 21098318
DOI: 10.1200/JCO.2010.30.1077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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