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Comprehensive characterization of human alveolar epithelial cells cultured for 28 days at the air-liquid interface

2 Jul 2025

Abstract excerpt

Lung epithelia are exposed to various substances in the atmosphere through breathing. To investigate the mechanisms and treatments for respiratory diseases caused by these substances, robust in vitro lung epithelial models are essential. This study aimed to develop an in vitro alveolar epithelial model using primary human pulmonary alveolar epithelial cells (HPAEpiCs). HPAEpiCs were cultured at an air-liquid...

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PMID: 40595111
DOI: 10.1038/s41598-025-07219-8

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