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Oropouche virus infects human trophoblasts and placenta explants

1 Jul 2025

Abstract excerpt

Clinical and epidemiologic evidence from the 2023–24 outbreak of Oropouche virus (OROV) has demonstrated increased severity in clinical disease and adverse pregnancy outcomes including miscarriage, stillbirth, and neonatal demise. Serological evidence suggests vertical transmission of OROV may be responsible. OROV has not been studied in the context of pregnancy and has an unknown ability to infect the relevant...

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PMID: 40593852
DOI: 10.1038/s41467-025-61138-w

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