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Next-generation sequencing of targetable gene fusions in radioiodine-refractory thyroid cancer: a multicenter study

26 Jun 2025

Abstract excerpt

We aimed to determine the prevalence and clinical significance of targetable gene fusions in patients with radioiodine-refractory thyroid cancer. This multicenter retrospective cohort study enrolled 111 patients from five tertiary medical centers, with molecular profiling performed using targeted next-generation sequencing. The analysis revealed that 58 (52.3%) patients possessed BRAFV600E mutation, while 25...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40569242
DOI: 10.1530/erc-25-0089

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