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Article

Alpha-1 Antitrypsin Deficiency and Bronchial Asthma: Current Challenges.

Biomolecules - 3 Jun 2025

Lopez-Campos José Luis, Muñoz-Sánchez Belén, Ferrer-Galván Marta, Quintana-Gallego Esther

Abstract excerpt

Alpha-1 antitrypsin deficiency (AATD) is a rare genetic condition classically associated with pulmonary emphysema and liver disease. However, the potential link between AATD and other respiratory diseases, particularly bronchial asthma, remains poorly understood and highly debated. This narrative review explores the current evidence regarding the epidemiological, clinical, and pathophysiological relationship...

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Identifiers

PMID: 40563447
DOI: 10.3390/biom15060807
PMCID: PMC12191358

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