Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sleep apnea among individuals with Alpha-1 antitrypsin deficiency-associated lung disease.

Respiratory medicine - 1 Sept 2025

Holm Kristen E, Sandhaus Robert A, Allison Sheri, Schroth Terri, McCathern Jean, Strange Charlie

Abstract excerpt

PURPOSE: Alpha-1 antitrypsin deficiency (AATD) is a genetic condition that has high rates of associated COPD. We explored whether obstructive sleep apnea (OSA) diagnosis, excessive sleepiness, and OSA risk scores differ by AATD genotype. PROCEDURES: A cross-sectional survey was completed by individuals with AATD-associated lung disease. Multivariate logistic regression was used to examine the association of...

Topics

Humans
alpha 1-Antitrypsin Deficiency
Male
Female
Middle Aged
Cross-Sectional Studies
Sleep Apnea, Obstructive
Genotype
Adult
Body Mass Index
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pulmonary Disease, Chronic Obstructive

Aged

Disorders of Excessive Somnolence

Source

Identifiers

PMID: 40550287
DOI: 10.1016/j.rmed.2025.108217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-40550287-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sleep apnea among individuals with Alpha-1 antitrypsin deficiency-associated lung disease.PMID 40550287Read ↗

Understanding the genetics of chronic obstructive pulmonary disease, α1-antitrypsin deficiency, and implications for clinical practice.Semantic proximity Read ↗

Advances in managing COPD related to α1 -antitrypsin deficiency: An under-recognized genetic disorder.Semantic proximity Read ↗

Recent advances in understanding and treating COPD related to α1-antitrypsin deficiency.Semantic proximity Read ↗

The Distribution of Alpha-1 Antitrypsin Genotypes Between Patients with COPD/Emphysema, Asthma and Bronchiectasis.Semantic proximity Read ↗

Alpha-1 antitrypsin deficiency: whom to test, whom to treat?Semantic proximity Read ↗

The prevalence of alpha-1 antitrypsin deficiency among patients found to have airflow obstruction.Semantic proximity Read ↗

Alpha-1 Antitrypsin Deficiency and Bronchial Asthma: Current Challenges.Semantic proximity Read ↗

Alpha-1 Antitrypsin Deficiency in COPD Patients: A Cross-Sectional Study.Semantic proximity Read ↗

Alpha-1 antitrypsin deficiency in bronchiectasis: Evidence for an overlooked entity beyond COPD: A retrospective observational study.Semantic proximity Read ↗

SZ alpha-1 antitrypsin deficiency and pulmonary disease: more like MZ, not like ZZ.Semantic proximity Read ↗

Clarifying the Risk of Lung Disease in SZ Alpha-1 Antitrypsin Deficiency.Semantic proximity Read ↗

Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea SubtypeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.