Article
The prevalence of alpha-1 antitrypsin deficiency among patients found to have airflow obstruction.
COPD - 1 Aug 2012
Rahaghi Franck F, Sandhaus Robert A, Brantly Mark L, Rouhani Farshid, Campos Michael A, Strange Charlie, Hogarth Douglas Kyle, Eden Edward, Stocks James M, Krowka Michael J, Stoller James K
Abstract excerpt
INTRODUCTION: Alpha-1 antitrypsin deficiency (AATD) is a genetic disease that may be manifested by chronic obstructive pulmonary disease. Despite professional society guidelines that recommend broad testing of at-risk individuals, fewer than 10% of affected individuals have been identified. The goals of this study were to estimate the frequency of abnormal AAT genotypes among patients found to have fixed airflow...
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