Article
The Effects of Specific Gut Microbiota on Hyperuricemia — A Mendelian Randomization Analysis and Clinical Validation
1 Jun 2025
Abstract excerpt
Background: Hyperuricemia (HUA) is a metabolic disorder caused by an imbalance between uric acid (UA) production and excretion. It is closely associated with various diseases, including gout and kidney disease. The intestines play a significant role in UA excretion, and emerging evidence suggests that gut microbiota modulate UA excretion and degradation. However, the specific functional microbial biomarkers and...
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