Article
The Effects of Specific Gut Microbiota and Metabolites on IgA Nephropathy-Based on Mendelian Randomization and Clinical Validation.
Nutrients - 22 May 2023
Wang Fang, Li Ning, Ni Siming, Min Yu, Wei Kang, Sun Hongbin, Fu Yuqi, Liu Yalan, Lv Dan
Abstract excerpt
BACKGROUND: Although recent research suggests that alterations in gut microbiota and metabolites play a critical role in the pathophysiology of immunoglobulin A nephropathy (IgAN), the causal relationship between specific intestinal flora and metabolites and the risk of IgAN remains unclear. METHOD: This study employed Mendelian randomization (MR) to investigate the causal association between gut microbiota and...
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