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Effects of obesity‐associated plasma markers on adipose stem cell function and epigenetic regulation

16 Jun 2025

Abstract excerpt

OBJECTIVE: This study investigates the correlations between obesity-related plasma markers and epigenetic/inflammatory changes in white adipose tissue (WAT), focusing on adipose-derived stem cells (ASCs). We hypothesize that obesity modulates histone H3K27 marks, modified by demethylases (lysine-specific demethylase 6A and 6B [KDM6A/KDM6B]) and acetylases (CREB-binding protein [CREBBP]/histone acetyltransferase...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 40518865
DOI: 10.1002/oby.24321

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