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Article

A single-nucleotide variant conditions the ability vs. inability of Propionibacterium freudenreichii to utilize L-lactate.

Applied and environmental microbiology - 23 Jul 2025

Cocuzzi Riccardo, Turgay Meral, Schmidt Remo S, von Ah Ueli, Bachmann Hans-Peter, Weisskopf Laure, Fröhlich-Wyder Marie-Therese

Abstract excerpt

Propionibacterium freudenreichii (P. freudenreichii) has various biotechnological applications, notably in the ripening of Swiss-type cheese, where it utilizes the two enantiomers of lactate as the main carbon source, contributing to flavor development and eye formation. Here, we genotypically characterized two P. freudenreichii strains unable to catabolize L-lactate through whole-genome sequencing and variant...

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Identifiers

PMID: 40503885
DOI: 10.1128/aem.00599-25
PMCID: PMC12285252

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