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Article

Longitudinal associations between medication use and phenotypic aging: insights from the Baltimore longitudinal study of aging.

The journals of gerontology. Series A, Biological sciences and medical sciences - 24 Jul 2025

Tang Bowen, Kuo Perry, Moore Ann Zenobia, Thambisetty Madhav, Ferrucci Luigi, Hägg Sara

Abstract excerpt

BACKGROUND: Limited population-based data exist on the association between medication use and changes in phenotypic aging. This study investigated these associations using data from the Baltimore Longitudinal Study of Aging. METHODS: Phenotypic aging (PA) markers were constructed using the Klemera-Doubal method across four domains: body composition (structural and metabolic changes), energetics (energy generation...

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Identifiers

PMID: 40498559
DOI: 10.1093/gerona/glaf128
PMCID: PMC12756985

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