Article
Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals.
The journals of gerontology. Series A, Biological sciences and medical sciences - 13 Nov 2019
Earls John C, Rappaport Noa, Heath Laura, Wilmanski Tomasz, Magis Andrew T, Schork Nicholas J, Omenn Gilbert S, Lovejoy Jennifer, Hood Leroy, Price Nathan D
Abstract excerpt
Biological age (BA), derived from molecular and physiological measurements, has been proposed to better predict mortality and disease than chronological age (CA). In the present study, a computed estimate of BA was investigated longitudinally in 3,558 individuals using deep phenotyping, which encompassed a broad range of biological processes. The Klemera-Doubal algorithm was applied to longitudinal data...
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