Article
A roadmap to build a phenotypic metric of ageing: insights from the Baltimore Longitudinal Study of Aging.
Journal of internal medicine - 1 Apr 2020
Kuo P-L, Schrack J A, Shardell M D, Levine M, Moore A Z, An Y, Elango P, Karikkineth A, Tanaka T, de Cabo R, Zukley L M, AlGhatrif M, Chia C W, Simonsick E M, Egan J M, Resnick S M, Ferrucci L
Abstract excerpt
Over the past three decades, considerable effort has been dedicated to quantifying the pace of ageing yet identifying the most essential metrics of ageing remains challenging due to lack of comprehensive measurements and heterogeneity of the ageing processes. Most of the previously proposed metrics of ageing have been emerged from cross-sectional associations with chronological age and predictive accuracy of...
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