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Fecal microbiome profiling of children with Shigella diarrhea from low- and middle-income countries

11 Jun 2025

Abstract excerpt

ABSTRACT Shigella is one of the leading pathogens causing diarrhea in children globally. Stool culture remains the standard for diagnosing Shigella infections; however, quantitative PCR (qPCR) offers greater sensitivity. In this study, we evaluated the fecal microbiomes of 27 diarrheal children with and without Shigella identified by culture and quantitative PCR, respectively, aiming to characterize the fecal...

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PMID: 40497681
DOI: 10.1128/spectrum.00573-25

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