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Article

Direct Detection of Shigella in Stool Specimens by Use of a Metagenomic Approach

8 Nov 2017

Abstract excerpt

ABSTRACT The underestimation of Shigella species as a cause of childhood diarrhea disease has become increasingly apparent with quantitative PCR (qPCR)-based diagnostic methods versus culture. We sought to confirm qPCR-based detection of Shigella via a metagenomics approach. Three groups of samples were selected from diarrheal cases from the Global Enteric Multicenter Study: nine Shigella culture-positive and...

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PMID: 29118177
DOI: 10.1128/jcm.01374-17

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