Clinical and sociodemographic correlates of emergent or evolving HIV drug resistance in low viral load specimens in British Columbia, Canada.

doi:10.1016/j.jcv.2025.105807

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Article

Clinical and sociodemographic correlates of emergent or evolving HIV drug resistance in low viral load specimens in British Columbia, Canada.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2025

Sudderuddin Hanwei, Beelen Charlotte Johanna, Li Jenny, Zhang Wendy, Murray Melanie C M, Lima Viviane D, Montaner Julio S G, Brumme Chanson J

Abstract excerpt

BACKGROUND/METHODS: Treatment guidelines recommend genotypic HIV drug resistance testing (DRT) at virologic failure, typically for plasma viral loads (pVL) > 1000 HIV RNA c/mL. In some settings, DRT can be performed on low viral load (LVL) samples (pVL of 50-250 c/mL); however, such testing is resource-intensive and its clinical benefit is unclear. Therefore, we investigated the frequency and factors associated...

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Topics

Humans
HIV Infections
British Columbia
Drug Resistance, Viral
Viral Load

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Female

Adult

Middle Aged

Anti-HIV Agents

Genotype

HIV-1

Young Adult

Sociodemographic Factors

Aged

Adolescent

Source

Open in PubMed

Identifiers

PMID: 40460587
DOI: 10.1016/j.jcv.2025.105807

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