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Article

A cell-ECM screening method to predict breast cancer metastasis.

Integrative biology : quantitative biosciences from nano to macro - 1 Feb 2015

Barney L E, Dandley E C, Jansen L E, Reich N G, Mercurio A M, Peyton S R

Abstract excerpt

Breast cancer preferentially spreads to the bone, brain, liver, and lung. The clinical patterns of this tissue-specific spread (tropism) cannot be explained by blood flow alone, yet our understanding of what mediates tropism to these physically and chemically diverse tissues is limited. While the microenvironment has been recognized as a critical factor in governing metastatic colonization, the role of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25537447
DOI: 10.1039/c4ib00218k
PMCID: PMC4323858

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